Home Organizations South Carolina Every cause Civil rights and advocacy 82 Environment and climate 352 Labor unions and worker centers 167 Housing and homelessness 474 Immigrant services and rights 19 Food banks and hunger 184 Legal aid 25 Voting and civic participation 27 Community health and reproductive care 54 LGBTQ+ services and rights 8 Criminal justice reform and reentry 57 Civil rights and advocacy (82) Organization City Type Revenue National Association For Gun Rights IncEIN 54-2015951 · filings Greenville Advocacy, 501(c)(4) $11.0 million Mother Emanuel Memorial FoundationEIN 82-1776426 · filings Charleston Charity, 501(c)(3) $3.1 million Disability Rights South Carolina IncEIN 58-1355302 · filings Columbia Charity, 501(c)(3) $2.5 million American Civil Liberties Union Of South Carolina Foundation IncEIN 27-1942832 · filings Columbia Charity, 501(c)(3) $1.9 million We Are FamilyEIN 57-1008020 · filings North Charleston Charity, 501(c)(3) $1.2 million South Carolina Appleseed Legal Justice CenterEIN 57-1035023 · filings Columbia Charity, 501(c)(3) $716,979 Palmetto State Abortion FundEIN 87-3822784 · filings Columbia Charity, 501(c)(3) $601,369 Daybreak IncEIN 57-0760670 · filings Columbia Charity, 501(c)(3) $587,907 Alliance For Full AcceptanceEIN 57-1072394 · filings N Charleston Charity, 501(c)(3) $499,958 Princetonians For Free SpeechEIN 85-3710034 · filings Johns Island Charity, 501(c)(3) $451,062 Isonomy IncEIN 87-4768307 · filings Columbia Charity, 501(c)(3) $198,511 3 Kings ProjectEIN 85-1778660 · filings Orangeburg Charity, 501(c)(3) $195,876
The 82 largest →
Environment and climate (352) Organization City Type Revenue National Wild Turkey Federation IncEIN 57-0564993 · filings Edgefield Charity, 501(c)(3) $54.3 million Brookgreen GardensEIN 57-0380356 · filings Pawleys Isl Charity, 501(c)(3) $18.5 million National Wild Turkey Federation IncEIN 57-1059205 · filings Edgefield Charity, 501(c)(3) $15.8 million Lowcountry Land Trust IncEIN 57-0809313 · filings Charleston Charity, 501(c)(3) $12.6 million United States Endowment Forforestry And Communities IncEIN 20-5583324 · filings Greenville Charity, 501(c)(3) $10.2 million South Carolina Coastal Conservation League IncEIN 57-0887278 · filings Charleston Charity, 501(c)(3) $9.6 million Naturaland TrustEIN 23-7293632 · filings Greenville Charity, 501(c)(3) $8.7 million Upstate ForeverEIN 57-1070433 · filings Greenville Charity, 501(c)(3) $7.3 million South Carolina Waterfowl AssociationEIN 57-0841167 · filings Pinewood Charity, 501(c)(3) $7.1 million Southeastern Wildlife Exposition IncEIN 31-1491910 · filings Charleston Charity, 501(c)(3) $5.7 million Heritage Preservation Trust IncEIN 81-5237557 · filings Edgefield Charity, 501(c)(3) $4.4 million South Carolina Rural Water AssociationEIN 57-0646037 · filings Columbia Charity, 501(c)(3) $3.7 million
The 300 largest →
Labor unions and worker centers (167) Organization City Type Revenue South Carolina Farm Bureau FederationEIN 57-0473090 · filings Cayce Labor organization, 501(c)(5) $11.2 million International Brotherhood Of TeamstersEIN 57-0315637 · filings West Columbia Labor organization, 501(c)(5) $4.5 million International Brotherhood Of Electrical WorkersEIN 57-0187390 · filings North Charleston Labor organization, 501(c)(5) $2.1 million Plumbers & Pipefitters Lu 421 Labor Management FundEIN 58-2442647 · filings N Charleston Labor organization, 501(c)(5) $1.4 million International Association Of Sheet Metal Air Rail & TransportationEIN 57-0275684 · filings N Charleston Labor organization, 501(c)(5) $1.2 million Ironworkers Joint Apprenticeship FundEIN 57-6027716 · filings N Charleston Labor organization, 501(c)(5) $833,921 International Union Of Operating Engineers 470EIN 57-0164925 · filings Graniteville Labor organization, 501(c)(5) $755,924 Sheet Metal Workers Local 399 JatcEIN 57-0792612 · filings Walterboro Labor organization, 501(c)(5) $532,389 International Association Of Heat & Frost Insulators & Allied WorkersEIN 57-0518341 · filings North Augusta Labor organization, 501(c)(5) $479,013 Laborers International Union Of North AmericaEIN 57-0746333 · filings West Columbia Labor organization, 501(c)(5) $429,971 National Rural Letter Carriers AssociationEIN 23-7235219 · filings Greenville Labor organization, 501(c)(5) $408,663 American Postal Workers UnionEIN 57-0481225 · filings Columbia Labor organization, 501(c)(5) $317,492
The 167 largest →
Housing and homelessness (474) Organization City Type Revenue Presbyterian CollegeEIN 57-0314408 · filings Clinton Charity, 501(c)(3) $76.7 million Cahec Management IncEIN 84-3628117 · filings Columbia Charity, 501(c)(3) $37.4 million Kiawah Island Community Association IncEIN 57-0713010 · filings Kiawah Island Advocacy, 501(c)(4) $25.9 million Community Services Associates IncEIN 57-0888471 · filings Hilton Head Advocacy, 501(c)(4) $22.1 million One-eighty PlaceEIN 57-0789483 · filings Charleston Charity, 501(c)(3) $18.2 million Eastern Carolina Homelessness Organization IncEIN 83-0421712 · filings Myrtle Beach Charity, 501(c)(3) $13.7 million Homes Of Hope IncEIN 57-1069688 · filings Greenville Charity, 501(c)(3) $9.1 million Southeastern Housing And Community DevelopmentEIN 31-1480295 · filings Barnwell Charity, 501(c)(3) $8.8 million Habitat For Humanity Of Horry County IncEIN 57-0912014 · filings Myrtle Beach Charity, 501(c)(3) $7.7 million Greenville Housing FundEIN 84-2931315 · filings Greenville Charity, 501(c)(3) $7.5 million South Carolina Community Loan FundEIN 01-0793507 · filings Charleston Charity, 501(c)(3) $7.3 million Habitat For Humanity International IncEIN 57-0827063 · filings Greenville Charity, 501(c)(3) $7.3 million
The 300 largest →
Immigrant services and rights (19) Organization City Type Revenue Alianza Hispana-hispanic AllianceEIN 27-1041624 · filings Greenville Charity, 501(c)(3) $991,064 Upstate InternationalEIN 57-1064857 · filings Greenville Charity, 501(c)(3) $209,133 Four Holes Indian Organization Edisto Tribal IncEIN 57-0570165 · filings Ridgeville Charity, 501(c)(3) $142,902 Refugee Hope Upstate IncEIN 92-2970370 · filings Salem Charity, 501(c)(3) $116,128 Refuge International IncEIN 88-3583464 · filings Gilbert Charity, 501(c)(3) $105,541 Pee Dee Indian Tribe Of South CarolinaEIN 57-0706888 · filings Mccoll Charity, 501(c)(3) $70,500 Carolina Immigrant Alliance IncEIN 83-0835985 · filings Rock Hill Charity, 501(c)(3) $17,887 Hope Table InternationalEIN 41-2787554 · filings Summerville Charity, 501(c)(3) — The Rtb ProjectEIN 41-3846128 · filings Lexington Charity, 501(c)(3) — Helping Hands Immigrant Community FoundationEIN 42-1839082 · filings Greenville Charity, 501(c)(3) — Visa Now Foundation IncorporationEIN 42-2225075 · filings Columbia Charity, 501(c)(3) — Cotton Patch Educational Foundation IncEIN 46-5678029 · filings Columbia Charity, 501(c)(3) —
The 19 largest →
Food banks and hunger (184) Organization City Type Revenue Harvest Hope Food BankEIN 57-0725560 · filings Columbia Charity, 501(c)(3) $50.5 million Senior Catering IncEIN 57-0777030 · filings Little Mtn Charity, 501(c)(3) $10.7 million Meals On Wheels Of Greenville IncEIN 57-0531378 · filings Greenville Charity, 501(c)(3) $6.0 million Mobile Meal Service Of Spartanburg County IncEIN 57-0653452 · filings Spartanburg Charity, 501(c)(3) $3.6 million East Cooper Meals On Wheels IncEIN 57-0804618 · filings Mt Pleasant Charity, 501(c)(3) $1.5 million The Spartanburg Soup Kitchen IncEIN 27-0530812 · filings Spartanburg Charity, 501(c)(3) $1.5 million Triune Mercy CenterEIN 20-0503624 · filings Greenville Charity, 501(c)(3) $1.4 million Clemson Community Care IncEIN 57-0868065 · filings Clemson Charity, 501(c)(3) $1.4 million Meals On Wheels Of Horry CountyEIN 26-3523060 · filings Myrtle Beach Charity, 501(c)(3) $1.3 million Meet The Needs CharlestonEIN 47-2703106 · filings Mt Pleasant Charity, 501(c)(3) $1.2 million Food Bank Of The LakelandsEIN 57-0775160 · filings Greenwood Charity, 501(c)(3) $1.1 million Loaves & FishesEIN 57-0931804 · filings Greenville Charity, 501(c)(3) $920,275
The 184 largest →
Legal aid (25) Organization City Type Revenue South Carolina Legal ServicesEIN 57-0485205 · filings Columbia Charity, 501(c)(3) $13.3 million Center For Heirs Property PreservationEIN 52-2452879 · filings N Charleston Charity, 501(c)(3) $7.9 million Pro Bono Legal Services IncEIN 20-0737728 · filings Charleston Charity, 501(c)(3) $1.2 million Low Country Legal VolunteersEIN 56-2202319 · filings Bluffton Charity, 501(c)(3) $1.2 million Charleston Legal AccessEIN 81-1013976 · filings North Charleston Charity, 501(c)(3) $967,395 Keep It Green - AdvocacyEIN 87-3732143 · filings Pawleys Isl Charity, 501(c)(3) $127,532 Neighborhood Legal Assistance IncEIN 57-0567401 · filings Charleston Charity, 501(c)(3) $6,814 Palmetto Innocence ProjectEIN 01-0552985 · filings Columbia Charity, 501(c)(3) — Heroes For ChildrenEIN 16-1749665 · filings Myrtle Beach Charity, 501(c)(3) — South Carolina Public Interest FoundationEIN 20-2475247 · filings Mount Pleasant Charity, 501(c)(3) — Aslan CommunityEIN 33-4553465 · filings Simpsonville Charity, 501(c)(3) — Sueno Americano For AllEIN 41-2586165 · filings Greenville Charity, 501(c)(3) —
The 25 largest →
Voting and civic participation (27) Organization City Type Revenue League Of Women Voters Of South Carolina IncorporatedEIN 57-6026436 · filings Columbia Charity, 501(c)(3) $113,321 Palmetto Center For Policyalternatives IncEIN 20-5985233 · filings Columbia Charity, 501(c)(3) $100,005 Grand Strand Community Law Enforcement CommitteeEIN 47-4352973 · filings Myrtle Beach Charity, 501(c)(3) $47,473 Winning America IncEIN 81-4786088 · filings Florence Charity, 501(c)(3) $34,085 Union County Sheriffs FoundationEIN 33-4374826 · filings Union Charity, 501(c)(3) $9,292 Upstate Action AllianceEIN 85-2876325 · filings Moore Charity, 501(c)(3) $6,539 Blue Starr Carolinas CorporationEIN 85-1912219 · filings Chester Charity, 501(c)(3) $338 Eastern Carolina Coalition Against Human TraffickingEIN 27-2435693 · filings Myrtle Beach Charity, 501(c)(3) — Cayce Beautification FoundationEIN 27-3130258 · filings Cayce Charity, 501(c)(3) — League Of Women Voters Of South CarolinaEIN 30-0540808 · filings Darlington Charity, 501(c)(3) — An Appeal To HeavenEIN 33-1687022 · filings Greenville Advocacy, 501(c)(4) — Voices Of AmericansEIN 39-3727298 · filings Charleston Advocacy, 501(c)(4) —
The 27 largest →
Community health and reproductive care (54) Organization City Type Revenue Caresouth Carolina IncEIN 57-0664826 · filings Hartsville Charity, 501(c)(3) $86.2 million St Francis Physician Services IncEIN 13-4290167 · filings Greenville Charity, 501(c)(3) $44.0 million Carolina Health Centers IncEIN 57-0650154 · filings Greenwood Charity, 501(c)(3) $40.1 million Low Country Health Care SystemEIN 58-2366697 · filings Fairfax Charity, 501(c)(3) $32.3 million Health Care Partners Of South Carolina IncEIN 57-0679807 · filings Conway Charity, 501(c)(3) $25.5 million Pee Dee Healthy Start IncEIN 58-2282396 · filings Florence Charity, 501(c)(3) $3.6 million Anderson Free Clinic IncEIN 57-0787584 · filings Anderson Charity, 501(c)(3) $3.4 million Barrier Islands Free Medical Clinic IncEIN 20-5628911 · filings Johns Island Charity, 501(c)(3) $2.4 million Unity Health On MainEIN 81-1080067 · filings Greenville Charity, 501(c)(3) $1.9 million Lowcountry Pregnancy CenterEIN 57-0838453 · filings N Charleston Charity, 501(c)(3) $1.8 million Pregnancy Center And Clinic Of Low Country IncEIN 57-0923523 · filings Hilton Head Charity, 501(c)(3) $1.6 million Columbia Free Medical ClinicEIN 57-0779279 · filings Columbia Charity, 501(c)(3) $1.5 million
The 54 largest →
LGBTQ+ services and rights (8) Organization City Type Revenue Alliance For Full AcceptanceEIN 57-1072394 · filings N Charleston Charity, 501(c)(3) $499,958 3 Kings ProjectEIN 85-1778660 · filings Orangeburg Charity, 501(c)(3) $195,876 Harriet Hancock Center FoundationEIN 57-0836466 · filings Columbia Charity, 501(c)(3) $141,361 Uplift And Outreach CenterEIN 84-2137645 · filings Spartanburg Charity, 501(c)(3) $74,336 Upstate Lgbt Chamber FundEIN 88-1951079 · filings Greenville Charity, 501(c)(3) $43,514 Upstate Pride ScEIN 27-1102951 · filings Greenville Charity, 501(c)(3) $38,066 Lc PrideEIN 84-3071985 · filings Beaufort Charity, 501(c)(3) $33,941 Affa ActionEIN 92-2710821 · filings N Charleston Advocacy, 501(c)(4) —
Criminal justice reform and reentry (57) Organization City Type Revenue JumpstartEIN 26-3023664 · filings Spartanburg Charity, 501(c)(3) $4.4 million Turn90EIN 46-0671501 · filings N Charleston Charity, 501(c)(3) $2.6 million Soteria World Outreach Ministries IncEIN 58-2475280 · filings Greenville Charity, 501(c)(3) $1.9 million Generation Group Homes Of Greenville IncEIN 57-0929065 · filings Simpsonville Charity, 501(c)(3) $1.5 million Sea Haven IncEIN 57-0713478 · filings Little River Charity, 501(c)(3) $1.5 million JumpstartEIN 47-4829697 · filings Spartanburg Charity, 501(c)(3) $636,455 Carolina Human ReinvestmentEIN 16-1777835 · filings Georgetown Charity, 501(c)(3) $535,357 Rainy Day FundEIN 85-4106379 · filings Columbia Charity, 501(c)(3) $269,888 Battered But Not BrokenEIN 80-0468545 · filings Chester Charity, 501(c)(3) $209,725 Speaking Down BarriersEIN 47-4421330 · filings Spartanburg Charity, 501(c)(3) $185,792 Circle Of Hope Ministries IncEIN 27-3678596 · filings Beaufort Charity, 501(c)(3) $124,602 Anchor MinistryEIN 82-2430458 · filings Rock Hill Charity, 501(c)(3) $116,513
The 57 largest →
Matched by IRS activity code and listed by the revenue on the organization's latest return. Inclusion is not an endorsement; check an organization's own site and filings before you give. Gifts to 501(c)(4) and 501(c)(5) organizations are not tax-deductible.
Source: IRS Exempt Organizations Business Master File . Updated Nov 9, 2026.